Endocrine Abstracts

Background: HIV-associated hypogonadism is a prevalent endocrine disorder, total testosterone (TT) test is not useful for its diagnosis, Endocrine Society clinical practice guidelines have recently proposed calculated free testosterone (FT) as screening test of hypogonadism in HIV infected men, but no clinical study has been published using this approach in HIV population to date. Our aim was to study prevalence and risk factors for hypogonadism in HIV-infected men using FT.</...

Objectives: Analyze the evolution of body mass index (BMI) and percentage of excess weight loss (PEWL) after bariatric surgery; compare adjustable gastric banding (LABG) vs laparoscopic gastric bypass (LGB).Methods: Cohort study. Inclusion criteria: all cases underwent laparoscopic bariatric surgery; n=89; 9 patients were excluded for incomplete follow up. Differences between the 2 groups were evaluated using the Student t-test; P&#6...

Aim: To study the prevalence of metabolic syndrome (MS) and its relation with ghrelin in old men.Material and methods: Prospective-population based study (2002–2005) in which 153 independently living men older than 70 y were included. Comorbidities, physical exam, BMI, blood pressure were recorded and blood sample taken for biochemical and hormonal determinations. Metabolic syndrome was defined using IDF criteria.Results: MS w...

Introduction: Several studies have suggested an association of thyrotropin (TSH) and free thyroxine (FT4) levels within the reference range with morbidity and mortality in the general population. Low free triiodothyronine (FT3) has also been associated with a poor prognosis in several conditions. However, the association between FT3 levels within the reference range and the risk of mortality in the general population remains uncertain.Methods: We evaluat...

PCOS is one of the most common cause of infertility in women during their reproductive years. High proportion of women with PCOS develop IR in peripheral tissues like skeletal muscle and adipose tissue, which may begin at the adolescent years when young women exhibit an increase in circulanting androgens. Studies in women with PCOS and animal models of PCOS have suggested alterations in insulin signaling pathways in skeletal muscle and adipose tissue. However, at the present t...

Introduction: Low-grade incomplete post-dexamethasone cortisol suppression in patients with adrenal incidentalomas, recently redefined as possible autonomous cortisol secretion (pACS), has been associated with increased cardiovascular events and mortality. However, prospective studies documenting cardiac abnormalities in these patients are lacking.Methods: In the context of ERGO trial NIH (NCT02611258), between July 2016 and September 2017, 71 consecutiv...

Introduction: Thyroid hormones modulate the insulin sensitivity and glucose metabolism. The interrelation between thyroid autoimmunity, thyroid function, glucose metabolism and cardiovascular risk factors remains uncertain.Methods: We recorded thyroid function tests, BMI, IR markers comprising the Homeostasis Model Assessment for insulin resistance (HOMA-IR and HOMA-B), the Quantitative Insulin Sensitivity Check Index (QUICKI), HISI (Hepatic Insulin Sens...

IntroductionMorbid obesity is a very prevalent disease, bariatric surgery being a fundamental pillar in its treatment.ObjectiveTo analyze the results of weight loss at 1 year in patients operated on gastric bypass and sleeve at the Regional University Hospital (HRU) of Malaga.MethodsRetrospective observational study, with a follow-up period of 1 year, of 215 patie...

BackgroundThe prevalence of malignancy among Bethesda category III (atypia of undetermined significance) cytologies is variable in different studies.ObjectiveThe aim of this paper is to evaluate the risk of malignancy of thyroid nodules classified as Bethesda III in our hospital.MethodsWe have reviewed the medical records of 146 patients who underwent FNA with Bet...

Purpose: Obesity is a chronic disease with a high risk of cardiovascular and metabolic comorbidities, hence a decrease > 5-10% of the initial body weight (BW) is essential to achieve improvement of cardiometabolic dysfunction. Bariatric surgery currently represents a valid therapeutic option in this clinical setting, especially in patients unresponsive to a dietary-nutritional approach. Obesity instigates adaptive hormone changes, yet the role of baseline hormone setting o...